Fast Volumetric Imaging for Live Cell Nanoscopy: Bringing Super-resolution to Life

Thesis director

Sandrine Lévêque-Fort is a CNRS Researcher Director at the Institute of molecular science (ISMO) in Paris Saclay University.  After a PhD on the development of a new acousto-optic imaging approach for imaging through scattering media in the Optical Lab of ESPCI in Paris, she became a postdoctoral fellow at Imperial College (London). She joined the CNRS in 2001 to develop new strategies in fluorescence microscopy for fluorescence lifetime imaging and more recently to bypass the diffraction limit with single molecule localization microscopy(SMLM). She aims at conceiving new imaging workflow, encompassing original optical concepts but also dedicated processing and alternative labelling, to address key biological questions in collaborations with biologists.

She has supervised/co-supervised 15 PhD students (5 now in academics, 4 in companies, 6 in post-docs (Stanford, Harvard, KTH, ITT, Institut Fresnel…). Among them she co-supervised 2 PhD in collaboration with Abbelight, which was created with her former PhD student, Nicolas Bourg. A common lab between ISMO and Abbelight has been created to further develop new avenues in single molecule imaging for live cells. She’s the recipient of the Irène Joliot Curie prize in 2020 (Women and company) and Knight of the french national order of merit.

She is co-author of more than 95 scientific articles from interdisciplinary research projects with high impact publications ( 2 Nature Photonics, 5 Nature communications, Science Advances, ACS Nano, PRL,PNAS..).  Her current developments to extend SMLM to live cell imaging  are supported by an Advanced ERC research Grant (11/2023-10/2028).

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